VHP Pass Box utilizes a flash vaporization process to generate hydrogen peroxide vapor (VHP), minimizing condensation and maintaining vapor-phase distribution - under controlled concentration, temperature, RH, and exposure parameters to achieve rapid and effective sterilization at a 6-log kill rate across exposed surfaces and defined load geometries. Leak-tight interlocked doors preserve cleanroom pressure and integrity, while an integrated catalytic converter decomposes residual H₂O₂ to <1 ppm, enabling rapid, residue-free aseptic transfer of heat-sensitive materials in GMP aseptic and containment applications.